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The GeneEd website is scheduled to be retired on March 31, 2019. Selected GeneEd content will be transferred to Genetics Home Reference, another online resource from the National Library of Medicine.

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DNA replication is the process by which a molecule of DNA is duplicated. When a cell divides, it must first duplicate its genome so that each daughter cell winds up with a complete set of chromosomes.

Images and animations are courtesy of the National Human Genome Research Institute's Talking Glossary (

Materials for Replication


DNA Polymerase - Making a new DNA Molecule From a Template

Description: An animation of replication showing DNA polymerase at work.

DNA Replication (Advanced Detail)

Description: A detailed animation of DNA replication

DNA Replication (Basic Detail)

Description: An animation of DNA Replication with basic details

Replication - Mechanism of Replication (Advanced)

Description: Watch this two minute animation of DNA replication.


What is DNA Replication?

Description: DNA replication is the process by which DNA makes a copy of itself during cell division.

Interactive Tutorials

A Half DNA Ladder is a Template for Copying the Whole

Description: An interactive Web site exploring basic concepts of the DNA replication through historical discovery

DNA Replication

Description: An interactive tutorial on DNA replication

DNA Sequence Editor Web App

Description: DNA Sequence Editor is a free web tool to analyze and edit your DNA sequence. Enter your DNA sequence and you can get the reverse, complementary or transcription sequence of your DNA. It can also translate your DNA sequence into possible amino acid sequences. It also help you to predict the DNA enzyme digestion result. Just select an enzyme from the list and you can get the size and sequence of each restricted DNA fragment. It is a useful web tool for molecular biology students and professionals. It is a great help for your molecular cloning work.

DNA Structure and Replication

Description: An interactive tutorial and practice exercises on DNA structure and replication

Heredity - Genetics

Description: Video and practice problems teaching core concepts of genetics, including DNA replication, transcription, translation, and genetic inheritance

Teacher Resources

DNA Replication: A case discussion of a landmark paper by Meselson and Stahl (Lesson Plans/Lesson Activities)

Description: An expert authored advanced in-class exercise involving literature assessment and detailed exploration of DNA replication

Molecular Genetics (Lesson Plans/Lesson Activities)

Description: Lesson guides and video slide show presentation on HIV viral replication and other molecular genetic topics