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Biostatistics

Biostatistics

The use of mathematics to investigate life science related problems

Biostatistics is a field of science that uses mathematics to investigate a number of life science related problems, including those pertaining to genetics, medicine, biology, agriculture, and environmental health.  Biostatistics uses algorithms, graphical tools, and statistical models and methods for a variety of applications, including the analysis of DNA sequence data and clinical trial results.

Materials for Biostatistics

Articles/Research

Biostatistics

Description: Information on how biostatistics are used in healthcare

Interactive Tutorials

Population Genetics and Evolution

Description: Information and practice problems on allelic frequency and the Hardy-Weinberg Law of Genetic Equilibrium

Labs & Experiments

Genetics of Organisms

Description: A virtual lab that uses fruit flies, mono- and dihybrid crosses, and statistics to teach concepts of inheritance

Teacher Resources

Build a Gel Electrophoresis Chamber (PDF 8,261.5 KB)

Description: Step-by-step instructions for building a gel electrophoresis chamber using inexpensive materials that are easily obtained from local hardware and electronics stores.

Colorful Electrophoresis

Description: A step by step guide to pouring and running a gel electrophoresis chamber using agar and food coloring from your kitchen pantry.

Drosophila Virtual Lab (Lesson Plans/Lesson Activities)

Description: Students learn and apply the principles of Mendelian inheritances by virtual experimentation with Drosophilia melanogaster (fruit fly). Students make hypotheses for monohybrid, dihybrid and sex-linked traits and test their hypotheses by selecting fruit flies with different visible mutations, mating them, and analyzing the phenotypic ratios of the offspring. Students learn how to collect, record, and organize their data.

Iceland’s Genetic Database: Good or Bad Idea? (PDF 28.17 KB, Lesson Plans/Lesson Activities)

Description: This lesson examines issues stemming from genetic databanks and population genetics studies.

Mendelian Genetics, Probability, Pedigree, and Chi-Square Statistics (Lesson Plans/Lesson Activities)

Description: A lesson that requires students to work through a series of questions pertaining to the genetics of sickle cell disease and its relationship to malaria. These questions will probe students' understanding of Mendelian genetics, probability, pedigree analysis, and chi-square statistics.

Mystery Yeast Mutation (PDF 381.48 KB, Lesson Plans/Lesson Activities)

Description: In this inquiry-based exploration students are asked to discover the nature of the mutation in a yeast strain by designing and carrying out their own experiments. Students are provided with a conundrum: the same mutant yeast strain can grow on one type of media plate but not another.

Retinoblastoma, Cystic Fibrosis, and Body Mass Index, Oh My! (PDF 196.72 KB, Lesson Plans/Lesson Activities)

Description: Building on their intuitive understanding of twin study correlations, students analyze subsets of data to determine how strong the environmental and genetic influences are for three different traits/conditions. Students use mean, standard deviation, and Pearson correlation coefficient to describe and make meaning of their data. They also graph their data and correlations, and compare the results from their subset of data to the results of a group using a different subset of the data.

Scitable Faculty Resources

Description: The Scitable faculty resource pages include a tool for creating virtual classrooms, the Scitable Faculty Discussion Group, and a variety of instructive courses for educators.

Statistics Education Web (STEW)

Description: STEW is a resource for peer-reviewed lesson plans for K-12 teachers. The statistical concepts follow the recommendations of the Guidelines for Assessment and Instruction in Statistics Education (GAISE) Report: A Pre-K-12 Curriculum Framework, Common Core State Standards for Mathematics, and NCTM Principles and Standards for School Mathematics.

Statistics Education Webinars

Description: Recorded web-based seminars on K-12 statistics education topics. The webinars aim to support teachers in their efforts to master statistics and incorporate core concepts into their classrooms.

The Probabilities of Problems: A Look at Inheritance (Lesson Plans/Lesson Activities)

Description: Students learn how to calculate the the probabilities of passing on certain genetic disorders and then evaluate case studies involving genetic testing.

Video

The Power of Numbers

Description: An engaging video introducing core statistical concepts such as mean, median, and standard deviation.